Tocilizumab (Actemra)

Actemra (Tocilizumab) is a monoclonal antibody medication designed to inhibit the interleukin-6 (IL-6) receptor, thereby reducing inflammation. It is commonly used in the treatment of autoimmune conditions such as rheumatoid arthritis, systemic juvenile idiopathic arthritis, and giant cell arteritis. Actemra is also utilized in managing cytokine release syndrome induced by certain cancer treatments. This specific formulation contains 200 mg of Tocilizumab in a 10 ml solution, intended for intravenous infusion.

Indications:

• Rheumatoid Arthritis (RA)
• Systemic Juvenile Idiopathic Arthritis (SJIA)
• Polyarticular Juvenile Idiopathic Arthritis (PJIA)
• Giant Cell Arteritis (GCA)
• Cytokine Release Syndrome (CRS)

Dosage and Administration:
Actemra is administered via intravenous infusion. The dosage varies based on the condition being treated, patient weight, and clinical response. It is essential to follow a healthcare professional’s guidance for dosing and administration. Prior to infusion, the solution should be diluted and administered by a qualified healthcare provider.

Side Effects:
Common side effects may include:

• Upper respiratory tract infections
• Headache
• Hypertension
• Elevated liver enzymes

Serious side effects can occur. Patients should be monitored for signs of infection, liver dysfunction, and gastrointestinal perforations. Consult the accompanying leaflet or a healthcare provider for a comprehensive list of side effects.

Precautions:

• Prior to initiating therapy, screen for latent tuberculosis.
• Monitor liver function tests regularly.
• Use with caution in patients with a history of gastrointestinal ulcers or diverticulitis.

Storage:

• Store in a refrigerator at 2°C to 8°C (36°F to 46°F).
• Do not freeze.
• Keep the vial in the outer carton to protect from light.

Manufacturer:
Roche

Note:
This product requires a prescription and should be used under the supervision of a qualified healthcare professional.

Disclaimer: The information provided here is for educational purposes only and should not replace professional medical advice. Always consult with a healthcare provider for medical guidance.